Current Trends in Chemotherapy for Pediatric Brain Tumor Essay

Current Trends in Chemotherapy for Pediatric idea Tumor - Essay ExampleDue to this, medical professionals have designed choice chemotherapy treatments that seek to address the side effects generated by the standard chemotherapy and improve the overall health of the paediatric patients. However, the effectiveness of the new trends such as metronomic therapy, circumventing the blood-brain barrier, and application of Bevacizumab monotherapy, raises interesting questions such as whether they can in effect handle the challenge of eliminating malignancies without posing greater threats to pediatric patients. Additionally, since the new methods are under experimental trials, their emerging is dependent on their efficacy, which has not yet been established.Cancer is one of the biggest challenges facing health care on a global basis. The impact of controlling the disease has affected the world economy. The American Cancer partnership report that the annual costs of crab louse in 2009 wer e estimated to be over $216.6 billion where $86.6 billion was fagged on direct medical costs whereas $130 billion was spent on indirect mortality. The American Cancer Society indicates that over 1,600 people die each day due to cancer complications. Brain tumor is the second most common cancer and the most frequent solid tumor in childhood, which account for 4.3 cases per 100,000 in the US (Gottardo & Gajjar, 2008). This paper will conduct an in-depth analysis of cancer in pediatric patients, giving special focus to brain tumors and the emerging chemotherapy treatment trends being administered to fight cancer in pediatric patients.According to Cabrera and Schub (2014), the most common brain neoplasms in children, and medulloblastoma, which account for 20-30% of all brain tumors in pediatric population. Although childhood cancer is relatively uncommon, the disease is still a persistent issue among the cancer patients it affects. Childhood Cancer states that Cancer is the second lead ing

Trying times for President Clinton during the sex sandal with monica Term Paper

Trying times for President Clinton during the sex sandal with monica lewinsky - barrier Paper ExampleThe impeachment of the former chairwoman came as a result of the scandal and a equity suit that was filled by Paula Jones (Neal, 2005135). This served as the second impeachment of a hot seat in power in the United States of America after the impeachment of the former president Andrew Johnson in the year 1868 (Neal, 2005136). When the impeachment proceedings were brought forward against the president in 1998 several issues were raised against the governmental processes. While some scholars took the matter lightly, separates argued that sexual conduct is a serious offense and is adequate to remove an elected president from the office. Those in support of the president argued that president just like any citizen of the United States have the right to privacy. They also stated that many other former presidents like John F. Kennedy, Roosevelt as well as Warren G. Harding had been linke d to extensive adulterous sexual activity but their sexual conduct was not made available to the public. As spy by Chapman (2010 99), the European observers were surprised that Americans engaged in impeachment proceedings against Bill Clinton because he lied slightly his sexual conduct. In their course, they stated that just like any citizen of America would avoid the truth most his sexual fidelity and so Bill Clinton will. In the impeachment case against Clinton, separation of power prevailed through the proceedings. In this context, the act of not telling the truth with respect to the sexual misconduct does not constitute complete evidences necessary for impeachable offenses as defined by the constitution of the country as high crimes and misdemeanors (Chapman, 201099). In this argument therefore, the impeachment against the president seemed partisan and was seen as an attempt by the legislative body to extend its powers and responsibility past the boundary. jibe to Chapma n (2010100), the charges that the former president faced were not worth impeachment because they did not grow from the failure of the president with catch to the state functions. However, the failure was from his personal life which is different from his public and political life. These differences in arguments divided the legislature and there was a clear boundary in terms of opinions between the republicans and the democrats. The question of what could constitute impeachment against a president had dominated the list of issues during Clintons administration. However, the fact that sex act was dominated by the Republicans presented a nemesis to the former president since the issue had taken political angle dividing the house into pro and against impeachment camps. It is this time that the congress dominated by Republicans appointed a counsel to investigate the financial backgrounds of the president (Kogan & Kelso, 2009 308). The counsel which was headed by Kenneth Starr was give n further responsibilities to investigate the scandal surrounding the former president and the white house intern, Monica Lewinsky. In close analysis of the unfolding events, it is clear that the push for the investigations and the impeachment of the former president was more political than legal. This is because the political enemies took the opportunity finish him politically. The trouble began when it became apparent that the intern, Monica had told

Project management Case Study Example | Topics and Well Written Essays - 1500 words

Project charge - side Study ExampleUtilisation Utilization = veritable output/ Design might In this illustration the veridical output is 12,000kg and fleshed capacity of 20,000kg. Utilization will be 12,000/20,000*100%= 60%. 60% utilization determine the effective capacity since if the plant is not turned on, then the effective capacity is zero. Ultimately, the dry cleaner designs will have some redundancies which lead to simple de-bottlenecking adding to capacity. v. Efficiency Efficiency is the existent output as determined through a percent of effective capacity. Hence, it is given as actual output / effective capacity. In this case study, efficiency will be (12,000/16,000) * 100% = 75%. (b) Managing Actual Output, Utilisation and Efficiency of the resources available The concern in the dry modify business is more on productivity that relates to competitiveness. The business will not be able to earn greater profit or charge a lower price. There is need for the business to increase its efficiency from 75% to all over 80% to boost operational efficiency whenever probable. Utilization as well is at 60% which is low. The solutions to increase utilization is through keeping the dry cleaning equipment in proper operational conditions, correcting quality problems, lessen bottlenecks and training of employees (Krajewski & Ritzman 2005). In order to increase the actual output, the federation must use a benchmarking method acting which measures capacity from choice of one not requiring adjustment or constant updates. The dry cleaning company eject benchmark the existing operational efficiency against other efficient dry cleaners in the locality whether in emerging or mature markets. The next step is to evaluate the efficiency of induce process to point out areas requiring improvement. Finally, the company can develop solutions meant to increase performance in these areas. This can include checking the speed of receipt of garments, sorting, cleaning, dryin g and packaging of cleaned clothes. Increasing the hours worked for each employee is one input which should be change magnitude to over 70% but by not increasing the number of employees to run the dry cleaning business (Krajewski & Ritzman 2005). The gains or losses must be tracked and performance standards established. The company should also develop worksheets capturing weekly, monthly and yearly data. Question 2 Devise and implement a brief visualise management plan to include a) Scope Management Scope management ensures clarity of project guidelines drawn from the trinity constraints such as cost, quality and time or schedule. For instance, a construction project synchronises the triple constraints to bait stakeholders perceptions of the success of the project. The scope of the project plan is monitored for probable changes if the scope of the project changes (Carly 2004). Agreeing on the scope ensures minimal rework which commits extra resources, time and cost overruns. In the case of the construction project, the prefabs will take 45 days to complete 4 houses. The expected project cost will be $4500. This project is evaluate to be made of cedar, cemented floor and Gall sheet roofing. The project will involve a fitted amount of work, only necessary work is carried out and work completed contributes to success of the construction project. The project will use existing technology since it is conventional (Thieraus et al 2009). The scope is clearly defined and the design

Attraction of Developed Markets for Emerging Market Brands Essay - 1

Attraction of Developed Markets for emergent Market Brands - Essay caseThis paper illustrates emergent markets as the markets or nations that have economies classified as being in their comparatively early development stages. These nations financial markets are less authentic compared to the major financial centers from all over the world. However, these markets are becoming increasingly integrated and sophisticated into the international and developed markets. The emerging markets spread crossways the globe and they differ extensively in their cultures, political, and economic behavior, as well as in factors that taunt their market growth. There has been an increasing attraction of the developed markets for the emerging market brands, though they face numerous challenges. Emerging markets face numerous challenges in their efforts of joining and competing in the developed markets. Agtmael stated that limited financial resources and the lack of international experience force t he emerging markets into becoming low-cost equipment manufacturers and abiders for the developed markets. The result is that the developed markets consider the products within the emerging markets as commodities and competitive, which leads to lower performance levels of the emerging markets, as well as the products within these markets. An additional obstacle for emerging markets venturing into the developed markets is that the developed markets are the negative stigma that consumers in these markets have on products from the emerging markets. Most of the consumers within the developed markets, as Agtmael states, are usually not willing to pay the market price of emerging commodities. This forces the companies within the emerging markets to lower their sales prices to venture sales. In return, the companies get little or no income, and at times, they make losses on the products they provide to the markets. The negative stigma of the developed markets makes it difficult for the br ands within the emerging markets to grow and join the developed markets. Emerging market brands seek to join the developed markets for various reasons. The different reasons are mainly to benefit from the great developed market. The main reason is to gain a greater market. Developed markets have to a greater extent customers compared to the emerging market. These markets provide a wider range of consumers for the products that exist within the markets compared to the developing markets. The developed markets usually have more participants, who are willing and committed to trading business activities.

To what extent should we make moral judgments about cultural practices Essay

To what extent should we bring in chaste concepts more or less ethnical practices from outside our own culture - Essay ExampleThose who recommend this pick out that the world is sharply divided into separate societies, sealed units, each with its own system of thought. They feel that the obedience and tolerance due from one system to a nonher forbids us ever to take up a critical position to any different culture. (Midgley, 69) According to this perspective, moralistic judgment is a kind of neologism valid only in its country of origin and the author terms this position ass moral isolationism. Midgley withal maintains that it is not forced upon individuals, and indeed makes no sense at all, to make moral judgment to the highest degree other cultures. Unlike the general thinking that such an attempt to make moral judgment about other cultures is a respectful attitude to other cultures, the author purports that one ejectnot respect what is entirely hidden to one and in th at respectfore it is not respectful attitude. Here, the author comes up with her central argument of the article and there is every reason to realize it as true and rational. As the author argues, it is essential for one to retire enough about another person or culture in order to come up with an evenhanded judgment about the culture or person. Therefore, Mary Midgley makes some essential arguments concerning moral judgment of other cultures in her article On Trying out Ones New Sword and a ruminative analysis of the article helps us in determining to what extent we should make moral judgments about cultural practices from outside our own culture. The article On Trying out Ones New Sword suggests a moral isolationism which lays down a general ban on moral reasoning with regard to making moral judgments about strange cultures. In order to establish her argument, the author makes use of some remote mannequin from the classical Japanese with a verb which means to try out ones new sw ord on a chance journeyer. According to this example, the Samurai is required to try out this new sword on any wayfarer who was not another Samurai, and this action could injure his honor, offend his ancestors, and even let down his emperor. Now when we essay of a custom like this, we may well reflect that we do not understand it and accordingly are not qualified to criticize it at all, because we are not members of that culture. But we are not members of any other culture either, except our own. So we extend the principle to cover all external cultures, and we seem therefore to be moral isolationists. (Midgley, 70) Midgley also deals with certain fundamental questions about moral isolationism with savoir-faire to making moral judgments about strange cultures. First of all, she examines whether the isolating barrier work both slipway or people in other cultures are equally unable to criticize others. According to her, outsiders can deliver perfectly good indictments, although i t makes more than two weeks to make them demining. Intelligent outsiders can progress in it, and in some ways will be at an advantage over the locals. But, if this is so, it must all the way apply to ourselves as much as anybody else. (Midgley, 70) The author also deals with the question whether the isolating barrier amidst cultures block praise as well as blame. It is important to make immaculate judgments about other

'ONLINE BASED COMPANY ANALYSIS AND BENCHMARKING' assignment Essay

ONLINE BASED COMPANY ANALYSIS AND BENCHMARKING duty assignment - Essay ExampleIt is for this reason that companies specialized in making bride dress have resorted to the internet to merchandise and hence sell their products.This reports main focus is develop a benchmark for examining the vanquish features and practices of brides dresses related breeding web pages so that they can be implemented in the live company (1K Bride company). However, before developing the benchmark for the analysis, the report offers a detailed literature review on the importance of internet-and particularly online communication- to the companies that specialize on bride dresses. In relation to the predetermined set of analytical criteria, the military rank of similar websites allow be undertaken (Clegg 1997, pg71). Both the strengths and weakness of each and every website will be highlighted, thereby giving much needed direction towards how the website of 1K Bride Dresses can be improved from its cur rent status to a much improved one. It is worth noting that 1K Bride Dresses falls under fashion and design industry in Australia thus much of the information gathered will be generalized with the assumptions that it fits well with 1K bride Company.This incredible growth of the digital universe means that more than simply the fact that individuals will be facing information fit on an unprecedented scale. This has implications for organizations concerning security, privacy, content management, intellectual property egis, data centre architecture, technology adoption and information management. According to the prediction made by IDC while almost 70% of the digital universe will be created by individuals, fashion and design firms will be responsible for the security, privacy, compliance and reliability of at least 85% of the same digital universe (Chung 2003, p11). In fact, according to IDC, information and privacy protection has become a boardroom

Questionnaire Essay Example | Topics and Well Written Essays - 1000 words - 2

Questionnaire - Essay Exampleder long time Drinking, 2006) Even though drinking is prohibited legally for under old aged children in legion(predicate) countries, it is a well cognise fact that many children usually consumes alcohol before they reaches the legal age for drinking. Under aged children many not have the maturity to control their emotions under the influence of alcohol and hence there is an change magnitude probability for them to engage in anti social activities and hence this research has immense importance in contemporary society.It is now commonly believed that the average young person will have seen 100,000 beer commercials between the age of two and eighteen (Hanson, 1997) The legal age for drinking is different in different countries ranging from 0 to 21. united States has the highest drinking age in the world where only those who have completed 21 years of age can drink legally. But incountries like China, Thailand and Viet Nam, there is no age restriction for drinking. In Austria Italy like countries the legal age for drinking is 16 whereas in Argentina and Israel it is 18 years. (Hanson, 1997)The questionnaire has been made uncomplicated and multiple choices were given to make the answer simple. The questions were made after discussions with some experts who have already study this subject. This research has been conducted mainly online. The questionnaire given at the end of this paper has been published on internet and the information collected from the respondents. Children who are from UK, between the ages of 12 18 were asked to participate in this research. This research was limited to UK children in order to standardize the results. Moreover around 2000 children of the same age group have been approached directly by visiting schools located at different parts of the country and collected information regarding their drinking habits. tout ensemble in all around 12500 data has been collected totally. The data has showed that arou nd 6750 (54%) of the respondents drink at least(prenominal) once daily. Around 3200